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99% Purity Raw Material Powder 53123-88-9 Rapamycin1
Chemical StocksRapamycinRapamycin Powder
Xi'an Homey Technology Co., Ltd.
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Product Description 99% Purity Raw Material Powder 53123-88-9 Rapamycin ItemSpecificationsAssay ,% 98.0% to 102.0% calculated trans- and cis-Stereoisomer of Sirolimus on the dried basis AppearanceWhite crystalline powder Loss On Dry Not More Than 0.50%Heavy Metals Not More Than 0.002%Individual Impurity Not More Than 1.0%Total Impurities Not More Than 2.0%Cis-Stereoisomer of Sirolimus Not More Than 5.0%Ethanol ≤5000PPMAcetonemia≤5000PPMRapamycin is produced by the soil bacterium Streptomyces hygroscopicus. The drug's name comes from Rapa Nui, the indigenous name of Easter Island, where the compound was originally discovered in soil samples in the 1970s.Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.ApplicationRapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway. Hot sale items:Product NameCAS No.Product NameCAS No.Lufenuron103055-07-8Toltrazuril69004-03-1Nitenpyram120738-89-8Biltricide Fenbendazole43210-67-9Tetramisole Hcl5086-74-8 Ponazuril9004-4-2Diclazuril101831-37-2Florfenicol73231-34-2Ivermectin70288-86-7Enrofloxacin Hcl112732-17-9Albendazole54965-21-8Mebendazole Package:Express delivery:Our Factory:Certificate:
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