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USP 99% Raw Powder Candesartan Cilexetil with CAS 145040-37-51
Essential Oil Balsam Fine ChemicalsCandesartan Cilexetil145040-37-5
Wuhan Recedar Biotechnology Co., Ltd.
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Product Description USP 99% raw powder Candesartan cilexetil with CAS 145040-37-5 Candesartan cilexetilCAS: 145040-37-5MF: C33H34N6O6MW: 610.66Chemical Properties White SolidUsage Ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. AntihypertensiveCandesartan cilexetil is an organic compound with the molecular formula C33H34N6O6. This product is white flakes with sweet taste. It is quickly broken down into the active metabolite candesartan in the body. Candesartan is an angiotensin II AT receptor antagonist. It antagonizes the contraction of angiotensin II by binding to vascular smooth muscle AT receptors, thereby reducing peripheral vascular resistance. Suitable for essential hypertension. Packagecarton drum with two plastic bags insideNet weight25KG/DrumStorageSealed in cool and dry place to avoid moisture and lightShelf life2 years when properly storedLead time1~3 days after confirmation ItemSpecificationAppearanceWhite to off-white powderClarity and Color solutionSolution in chlorofor at 5% is clear and colourlessThe1.HPLCThe retention time of major peak in the chromatogram of the test solution corresponds to that of the standard solution, as obtained in the procedure for prganic impurities by HPLC 2. IRSimilar to standardWaterNot more than 0.30%Residue on IgnitionNot more than 0.1%TinNMT 10ppmAzide by ICNMT 10ppmMelting range160oC~166oCHeavy MetalsNot more than 10 ppmAs< 1 ppmParticle size distribution90% <30 μm50% ≤10 μmOrganic impurities by HPLCEthyl Candesartan -NMT 0.15% Desethyl Candesartan -NMT 0.15%N2-Ethyl Candesartan Cilexei -NMT 0.15% Any unknown impurity -NMT 0.10%Total impurities -NMT 0.60%Assay by potentiometryNot less than 99.0% - 101.0% on dried basisOVI(organic volatile impurity)Methano -NMT 0.3%Ethanol -NMT 0.5% Diethyl ether -NMT 0.5% Aceton -NMT 0.5%Dichloromethan -NMT 0.06%Dimethylformamide -NMT 0.088%Microbiological Contarnination/gTotal aerobic microbial count -1000 cfuTotal combined moulds & yeasts-100 cfuOther specific micro organisms-Absent (E.Coli,Salmonella sp)NEMA&NDEA0.3ppm&0.18ppm More reports, please contact us freely.
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