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Skin Care Raw Material CAS 674-26-0 Dl Mevalonolactone1
Essential Oil Balsam Fine ChemicalsMevalonolactoneDl Mevalonolactone
Xi'an Harmonious Natural Biotechnology Co., Ltd.
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Product Description Skin care raw material CAS 674-26-0 DL Mevalonolactoneproduct nameDL Mevalonolactonecas674-26-0 Description:DL-Mevalonolactone is the δ-lactone form of mevalonic acid, a precursor in the mevalonate pathway. It induces depolarization and swelling, decreases NADPH content and aconitase (ACO) activity, and increases malondialdehyde (MDA) production in calcium-loaded rat brain mitochondria. DL-Mevalonolactone reverses decreases in glucose uptake induced by simvastatin (Item Nos. 10010344 | 10010345) in L6 myotubes. Tissue levels and urinary excretion of DL-mevalonolactone are increased in patients with mevalonic aciduria, a disorder characterized by a deficiency in mevalonic kinase activity.Application: -Mevalonolactone is used to:study the effect of statin on the prenylation of Ras and Rho GTPasesanalyse the isoprenoid biosynthesis pathways in Listeria monocytogenesstudy the the effects of statins on proliferation and migration of HUVECs (HGF-induced human umbilical vein endothelial cells)Analytical ItemsStandardAppearanceWhite crystalline powderIdentificationSimilar with the Reference SpectrumOptical Rotation-15.5°~ -17.5°Clearity & color of solutionClear & ColorlessHeavy Metals≤10ppmPb≤3ppmAs≤1ppmCd≤1ppmHg≤0.1ppm Related substancesTotal≤2.0% GSSG≤1.5% Loss on drying≤0.5% Residue on ignition≤0.1% Assay 98.0% - 101.0% Microbiology Total plate count≤1000cfu/g Yeast and mold count≤100cfu/g Total coli forms≤100cfu/g E. coliNegative/10g S. aureusNegative/10g SalmonellaNegative/10g
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