Chemical Intermediate Pnc-27 Purity Synthetic Peptides Pnc-27 Peptide¹

Product Description Chemical Intermediate Pnc-27 Purity Synthetic Peptides Pnc-27 PeptideDetailed Photos    Product Description Product Name:PNC-27Cas No.peptidesPurity:99%Formula weight:579.3Package:Foil BagMolecular formula:C30H54N6O5MOQ:1 Gram or 1 BoxEINECS:203-405-2delivery:8-12daysGrade StandardTop QualitySampleAvailiableShelf Life2 Years PNC-27 is a synthetic peptide primarily used for its anti-cancer properties. It is designed to target and bind to the HDM-2 protein, which is overexpressed in cancer cells. This binding leads to the formation of pores in the cancer cell membranes, resulting in cell necrosis and death. Importantly, PNC-27 selectively targets cancer cells without harming normal cells, making it a promising candidate for cancer therapy.The primary use of PNC-27 is in cancer research, where it has shown potential in treating various types of cancer, including acute myeloid leukemia (AML), breast cancer, and pancreatic cancer. Its mechanism of action involves binding to HDM-2 in a p53 peptide-like structure, which disrupts the function of HDM-2 and leads to the activation of p53, a tumor suppressor protein. This activation triggers pathways that result in the death of cancerous cells.Ongoing research continues to explore the applications and efficacy of PNC-27 in different cancer types, aiming to provide effective and less toxic treatment options for cancer patients PNC-27 is an anti-cancer peptide that has shown significant promise in cancer research. It is designed to bind to the HDM-2 protein, which is overexpressed in cancer cells. This binding leads to the formation of pores in the cancer cell membrane, resulting in cell necrosis and death.Structure and MechanismPNC-27 is composed of amino acid residues 12-26 from the HDM-2 binding domain of the p53 protein, linked to a membrane-penetrating sequence known as the membrane residency peptide (MRP). This structure allows PNC-27 to infiltrate cancer cells and exert its cytotoxic effects. It selectively targets cancer cells without harming normal cells, making it a potentially safer treatment option.ApplicationsPNC-27 has demonstrated effectiveness against a wide range of cancer types, including acute myeloid leukemia (AML), breast cancer, pancreatic cancer, melanoma, and others. In studies, PNC-27 has been shown to induce nearly 100% cell killing in cancer cells, while having no effect on healthy cells.Research and DevelopmentOngoing research continues to explore the potential of PNC-27 in different cancer models. It has been tested in both in vitro and in vivo studies, showing promising results in reducing tumor growth and prolonging survival in animal models. The peptide's ability to target cancer cells through a p53-independent pathway further enhances its therapeutic potential.Overall, PNC-27 represents an innovative approach in cancer treatment, offering a targeted and potentially less toxic alternative to traditional chemotherapy.    Packaging & Shipping  Payment Feedback Our Advantages Goods quality1. Product has COA, and HPLC report2. Our factory is ISO9001 standard3. Get good feedback from customers around the worldOEM service1. Redesign label, packing box as customer's requirement2. Cap color can be customizedShipping service1. Arrange goods within 24 hours after payment.2. Door to door shipping without customs clearance.3. Stealth packing discreet shipping4.100% delivery gurantee24 hours online response1. Reply your inquiry within 30 MINUTES2. Keep tracking goods and update information to customer ALL times 3. After-sale service anytimeFAQQ1: About the after-sale service of productsA: After purchasing the products from our factory, we have A professional technical team and after-sales team to serve you and solve all your problems in the futureQ2: Can I get some samples?A: Yes, we can provide samples, but the customer will pay the freight.Q3: How do I start paying?Payment can be made by Bitcoin,wire transfer or Western Union Q4: How to confirm product quality before placing an order?A: You can get free samples of some products. You just have to pay the shipping feeQ5: What is your MOQ?A: The minimum quantity we can order is 1kit.Q6: How to customize the product??A:You can send us your product specifications and requirements and we will produce products according to your requirements.  

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