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99% Pyridoxal Phosphate Powder CAS 54-47-71
Biochemical99% Pyridoxal Phosphate PowderCAS 54-47-7
Hefei July Biotechnology Co., Ltd.
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Product Description Product DescriptionPyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions. The Enzyme commission has catalogued more than 140 PLP-dependent activities, corresponding to ~4% of all classified activities. The versatility of PLP arises from its ability to covalently bind the substrate, and then to act as an electrophilic catalyst, thereby stabilizing different types of carbanionic reaction intermediates. Product NamePyridoxal PhosphateAppearanceWhite crystalline powderCAS No54-47-7Purity99%MFC8H10NO6PMolecular Weight247.14 FunctionPLP acts as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.The aldehyde group of PLP forms a Schiff-base linkage (internal aldimine) with the ε-amino group of a specific lysine group of the aminotransferase enzyme. The α-amino group of the amino acid substrate displaces the ε-amino group of the active-site lysine residue in a process known as transaldimination. The resulting external aldimine can lose a proton, carbon dioxide, or an amino acid sidechain to become a quinoid intermediate, which in turn can act as a nucleophile in several reaction pathways. In transamination, after deprotonation the quinoid intermediate accepts a proton at a different position to become a ketimine. The resulting ketimine is hydrolysed so that the amino group remains on the complex.ApplicationIn addition, PLP is used by aminotransferases (or transaminases) that act upon unusual sugars such as perosamine and desosamine.In these reactions, the PLP reacts with glutamate, which transfers its alpha-amino group to PLP to make pyridoxamine phosphate(PMP). PMP then transfers its nitrogen to the sugar, making an amino sugar.PLP is also involved in various beta-elimination reactions such as the reactions carried out by serine dehydratase and GDP-4-keto-6-deoxymannose-3-dehydratase (ColD).It is also active in the condensation reaction in heme synthesis.PLP plays a role in the conversion of levodopa into , facilitates the conversion of the excitatory neurotransmitter glutamate to the inhibitory neurotransmitter GABA, and allows SAM to be decarboxylated to form propylamine, which is a precursor to polyamines. Packaging & Shipping Packing1kg/bag ,25kg/bag;25kg/drum; according to your requirementsTransitFedex, TNT,DHL,EMS,and so on.PortShanghai/Tianjin/Dalian/Beijing/Xi'anLead Time3-5 working days upon received the payment For mass orders, it will be delivered by air or sea.Depending on your location, please allow 1-5 business days for your order to arrive.For small order, please expect 3-7 days by UPS DHL EMS.For mass order, please allow 5-8 days by Air, 15-30 days by Sea.Company Profile Hefei July Biotechnology Co.,ltd is trading system gradually mature stable, scale, expanding opening flexible, the godfather management, Its marketing network, good business reputation has been praised by customers. The company has already established marketing channels with many manufactures and customers all over the world.We are specialized in Chemical raw materials: API, Pharmaceutical intermediates, Plant extracts, Health care ingredient, Vitamin,Food additives and Cosmetic additives. These products are widely used in pharmaceutical industry, chemical industry, food industry and other industries. Welcome to consult us. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success!Exhibition FAQ 1. What's the MOQ?Usually1kg. It is based on the different product. Some are lg and some are 1 ton. Please be free to consult our salesman.2. What's the shipping time?If in stock, we will ship it out immediately. By FedEx will be 3~5 days to you.3. If I need less than the MOQ, is it possible? Yes. Please be free to consult our salesman.4. Can you supply the free sample?Usually it is possible. but the shipping cost be paid bycustomers. It based on the differentproduct.Please be free to consult our salesman.5. How to store the product? Store in cool and dry place. It must be in well closed containers. The shelf life will be 2 years.6. What's your main payment method?T/T, trade assurance, west union, money gram.7: Do you have COA, MSDS, co, Health certificate, form 9 or other certificate? Yes, we have. pls be free to contact us to get updated one.
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