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CIPDBChina IndustryChemicalsEssential Oil, Balsam & Fine Chemicals



Premium Quality Caffeic Acid Research Reagent CAS 331-39-51

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Essential Oil Balsam Fine ChemicalsHigh Quality AcidResearch Reagent Acid

Changsha Nutra-Y Biotechnology Co., Ltd

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Product Description  Function and efficacyCaffeic acid is widely distributed in a variety of Chinese herbal plants such as wormwood, thistle and honeysuckle. It belongs to phenolic acid compounds, and has pharmacological effects such as cardiovascular protection, anti-mutagenesis and anticancer, antibacterial and antiviral, lipid-lowering and glucose-lowering, anti-leukemia, immune regulation, gallbladder hemostasis and antioxidant. Caffeic acid can shrink and strengthen microvascular, reduce permeability, improve coagulation Chemicalbook and leukocyte platelet number, clinical often used in a variety of surgical and medical bleeding prevention and treatment, gynecological bleeding disease has significant effect, also used in cancer disease chemotherapy and radiotherapy and other causes of leukocyte thrombocytopenia symptoms, It also has certain curative effect on diseases such as essential thrombocytopenia and aplastic leukopenia. Caffeic acid is widely distributed in a variety of Chinese herbal plants such as wormwood, thistle and honeysuckle. It belongs to phenolic acid compounds, and has pharmacological effects such as cardiovascular protection, anti-mutagenesis and anticancer, antibacterial and antiviral, lipid-lowering and glucose-lowering, anti-leukemia, immune regulation, gallbladder hemostasis and antioxidant. Caffeic acid has the functions of hemostasis, anti-inflammatory, bacteriostasis, promoting wound healing, relieving spasmodic and so on. The drug can be used to treat gastrointestinal bleeding and other diseases, the use should pay attention to dose control and follow the doctor's advice.Step 1 Stop bleedingCaffeic acid has the effect of inhibiting fibrinolysis and increasing capillary permeability, thus playing the role of hemostasis. Treatment by oral or topical application of caffeic acid preparations.2. Anti-inflammatoryCaffeic acid can block the epoxidase pathway in the metabolism of arachidonic acid, reduce the synthesis of prostaglandin E2, and then play an anti-inflammatory role. For situations where there is an inflammatory response, it is recommended to reduce intake of foods that may exacerbate inflammation, such as foods high in sugar, to reduce symptoms.3. AntibacterialCaffeic acid can interfere with the synthesis of bacterial cell wall, resulting in bacterial growth is blocked, so it has a certain antibacterial effect.4. Promote wound healingCaffeic acid can enhance the phagocytosis of macrophages, accelerate the clearance of necrotic tissue and the formation of new granulation tissue, thus promoting wound healing. When dealing with open wounds, avoid premature closure of the wound in order to use caffeic acid to facilitate the natural repair process.5. Relieve spasmsCaffeic acid can stimulate the opioid receptors in the central nervous system, reduce the excitability of the nervous system, relieve the tension of smooth muscle, so it has the effect of antispasmodic. IntroductionCaffeic acid is an organic acid with molecular formula of c9h8o4 and molecular weight of 180.15. It is yellow crystal obtained from concentrated aqueous solution and monohydrate obtained from dilute aqueous solution. Decomposition point 223 ~ 225 °(softening at 194 °). Slightly soluble in cold water, easily soluble in hot water and cold ethanol. It can be safely used in cosmetics and has a wide range of antibacterial and antiviral activities. It can absorb ultraviolet rays. Low concentration is an additive that can inhibit skin type hair dyes, which is conducive to enhancing the strength of color.Function1) Caffeic acid has been shown to inhibit carcinogenesis, although other experiments show possible carcinogenic effects. It is also known as an antioxidant in vitro and also in vivo.2) Caffeic acid also shows immunomodulatory and antiinflammtory activity.3) Caffeic acid outperformed the other antioxidants, reducing aflatoxin production by more than 95 percent.4) The studies are the first to show that oxidative stress that would otherwise trigger or enhance Aspergillus flavus aflatoxin production can be stymied by caffeic acid.This opens the door to using natural anti- fungicide methods by supplementing trees with antioxidants.5) Another study also showed that CAPE suppresses acute immune and inflammatory responses and holds promise for therapeutic uses to reduce inflammation.6) Caffeic acid  also is  cosmetic whitening raw materials About us* The statements in this section have not been evaluated by the FDA or EFSA.References    1.Khan F, Bamunuarachchi NI, Tabassum N, Kim YM.J Agric Food Chem. 2021 Mar 17;69(10):2979-3004. doi: 10.1021/acs.jafc.0c07579. Epub 2021 Mar 3.PMID: 33656341    2.Muhammad Abdul Kadar NN, Ahmad F, Teoh SL, Yahaya MF.Molecules. 2021 Sep 9;26(18):5490. doi: 10.3390/molecules26185490.PMID: 34576959    3.Li XN, Shang NY, Kang YY, Sheng N, Lan JQ, Tang JS, Wu L, Zhang JL, Peng Y.Acta Pharmacol Sin. 2024 Feb;45(2):248-267. doi: 10.1038/s41401-023-01177-5. Epub 2023 Oct 13.PMID: 37833536   4.Chiang YF, Lin IC, Huang KC, Chen HY, Ali M, Huang YJ, Hsia SM.Biomed Pharmacother. 2023 Oct;166:115327. doi: 10.1016/j.biopha.2023.115327. Epub 2023 Aug 22.PMID: 37619480   5.Zhao X, Liu Z, Liu H, Guo J, Long S.Eur J Med Chem. 2022 Dec 5;243:114745. doi: 10.1016/j.ejmech.2022.114745. Epub 2022 Sep 9.PMID: 36152388

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