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Pharmaceutical Nootropics Bromantane Powder Bromantane1
Pharmaceutical IntermediateBromantaneBromantane Powder
Xi'an CQ-Moonlight Pharmaceutical Ltd.
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Product DescriptionPharmaceutical Nootropics Bromantane Powder BromantaneProduct DescriptionProduct DetailsProduct NameBromantaneCAS No.87913-26-6MFC16h20brnMW306.24AppearanceWhite PowderBromantane (CAS 54878-11-0), chemically known as *(1R,2S)-3-(4-bromophenyl)-N-[(1,1-dimethylethyl)amino]-2-methyl-2-propanamine*, is a unique psychostimulant and adaptogen with a molecular weight of 270.18 g/mol. This white crystalline powder exhibits dual dopaminergic and glutamatergic activity, originally developed in Russia as Ladasten? for asthenic conditions. With ≥98% HPLC purity, it demonstrates excellent solubility in ethanol (>50 mg/mL) and stability at room temperature (15-25°C) when protected from light. Its pharmacokinetic profile includes rapid absorption (T<sub>max</sub>: 1.5–2 hours) and a half-life of 6–8 hours, metabolized primarily via CYP2D6. Bromantane's non-addictive nature and lack of significant toxicity (LD<sub>50</sub> >1000 mg/kg in rats) make it a promising research compound for neuroenhancement and stress resilience studies.Application&FunctionMechanisms of Action:1.Dopamine Synthesis Upregulation: Increases tyrosine hydroxylase activity in the striatum (30–50% elevation in animal models);2.Glutamate Modulation: Enhances AMPA receptor trafficking without excitotoxicity;3.Adaptogenic Effects: Normalizes HPA axis function under stress;Clinical & Research Applications:1.Asthenia Treatment: Approved in Russia for fatigue (50–100 mg/day, 2-week courses);2.Cognitive Enhancement: Improves working memory in healthy volunteers (p<0.01 vs placebo);3.Neuroprotection: Reduces oxidative stress markers (MDA ↓40% in preclinical studies);4.Parkinson's Models: Preserves dopaminergic neurons (MPTP-induced toxicity).SpecificationCertificate of Analysis
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