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Gsh CAS 70-18-8 L-Glutathione Reduced Nutrional Supplement1
Pharmaceutical ChemicalsVitaminNutritional Supplement
HN Langyue Biotech Co., Ltd.
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Product Description GSH CAS 70-18-8 L-Glutathione reduced nutrional supplementProduct Information:Product Name:GlutathioneSynonyms:glutatiol;glutatione;glutide;glutinal;isethion;l-glutatione;N(N-L-.gamma.-Glutamyl-L-cysteinyl)glycine;n-(n-l-gamma-glutamyl-l-cysteinyl)-glycinCAS:70-18-8MF:C10H17N3O6SMW:307.32EINECS:200-725-4Assay:HPLC 99%Package:25kg/drum or customizedShelf life:24monthsStorage:Store in a cool, dry place, away from bright light and high temperature.Reduced glutathione (GSH) is a crucial antioxidant that supports healthy liver function. It is found in high concentrations incellular systems and plays a crucial role in detoxification of various substances. Glutathione (GSH) is a ubiquitous molecule found in many cells and tissues. The three amino acids present in GSH are glycine, cysteine, and glutamic acid.ApplicationL-Glutathione (GSH) reduced has been used in the elution buffer to elute GST (glutathione S-transferase)-fused proteins using glutathione-agarose beads.[2][3] It has been used to prepare a standard curve for GSH analyses.[4]May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.Biochem/physiol ActionsGlutathione (GSH) forms conjugates with various metabolites and xenobiotics. It acts as an important co-factor for various enzymes. GSH is involved in many metabolic and signaling pathways. Glutathione functions as a thiol buffer for cellular proteins like thioredoxins and metallothioneins. GSH is also involved in the regeneration of antioxidants like tocopherols and ascorbate.Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents. ITEMSPECIFICATIONRESULTTest MethodAppearanceWhite powderCompliesVisualOdor and tasteCharacteristicCompliesSensoryIdentificationMeet requirementsCompliesIRLoss on drying≤0.5%0.32%USP 40Residue on ignition≤0.1%0.04%USP 40Optical Rotation[α]D20: -15.5°~-17.5°°-15.8°°USP 40SolubilitySoluble in water, insoluble in ethanolCompliesVisualBulk density0.3~0.6g/ml0.43g/mlCP2015Tapped density0.4~0.9g/ml0.55g/mlCP2015Appearance of solutionClear and colorlessCompliesVisualTotal Heavy metals≤10ppmCompliesUSP 40Pb≤3ppmCompliesUSP 40As≤2ppmCompliesUSP 40Cd≤1ppmCompliesUSP 40Hg≤1ppmCompliesUSP 40Iron≤10ppmCompliesUSP 40Chloride≤200ppmCompliesUSP 40Ammonium≤200ppmCompliesUSP 40Sulfate≤300ppmCompliesUSP 40Total microbacterial count≤100CFU/gCompliesCP2015Yeast &Mould≤10CFU/gCompliesCP2015Escherichia Coli presenceNegativeNegativeCP2015SalmonellaNegativeNegativeCP2015S. aureusNegativeNegativeCP2015P. aeruginosaNegativeNegativeCP2015Total impurities≤2.0%1.1%USP 40Individual impurity(L-Glutathione Oxidized)≤1.5%0.9%USP 40Assay98.0%~101%98.8%USP 40ConclusionThe results conforms with the USP 40 standardQuality Control: We have advanced precision instruments and equipment ,so we can independently control product content, pesticide residue, physical and chemical properties, microorganisms, heavy metals and other quality indicators. Our goal is zero complaints.We have our own plant base. Weeding by hand, no pesticides or herbicides used. Control quality from the source.Packaging:The product is packed in 25kg or 10kg fiber drum.It should be stored in its original packing or in a suitable sealed container and kept in a clean and dry place. Storage conditions should preferably be a sheltered environment with limited temperature variations and low humidity levels. Direct contact with water or any other liquid will result in product caking. Under normal circumstances, the use of this product will not cause any undue health hazards. Precautions must be taken to prevent solid or liquid product to contact with skin or eyes.Customization ServiceR&D and Production: We specializes in the development of functional materials and has provided a number of development and improvement solutions.Granular Production: Our granulation and superfine pulverization can improve bulk density to filling capsules and tablets. and increase water solubility.Blending and Mixing
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