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China, Chinese 99% Purity Lyophilized Powder Thymosin Alpha 1 5mg/Vial Peptides CAS 62304-98-7¹ Industrial Products Supplier Manufacturer Details, price list catalog:

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Product Description Product Description Product Information Products Name: Thymosin Alpha 1CAS No.: 62304-98-7Purity: >99.0%Appearance: White Lyophilized powderReconstitution: Required Storage:After reconstitution store at 2°C - 8°CWHAT IS THYMONSIN ALPHA 1 α 1) ?Thymosin alpha 1 α 1) is a drug peptide that treats chronic hepatitis B and enhances immune system responsiveness. thymus α Stimulating peripheral blood lymphocyte mitogen promotes the maturation of T lymphocytes and increases the secretion of interfer by T cells after antigen or mitogen activation α, interfer γ And the levels of lymphokines such as interleukin-2 and interleukin-3, while increasing the level of lymphokine receptors on the surface of T cells. It is also possible to enhance the mixed lymphocyte response of allogeneic and autologous humans by activating CD4 cells. Thymic peptide α 1 may increase the aggregation of pre NK cells, while interfer can enhance their cytotoxicity. In vivo experiments have shown that thymosin alpha1 can increase the expression level of interleukin-2 receptors in mouse lymphocytes activated by concanavalin A, while also increasing the secretion level of interleukin-2. Current thymic peptides on the market α The synthesis preparation method has a long synthesis cycle and high production cost, which is not conducive to the large-scale production of bivaludine.Pharmacological effects:Thymic peptide α 1 is composed of 28 amino acid peptides. In 1977, a single peptide thymus was first isolated from thymosinfraction5 (TF5) in thymosin component 5 α 1. Its activity is 10-1000 times higher than TF5, and its molecular weight is 3108KD. thymus α 1 is a highly conserved acid peptide structure, mainly distributed in thymic tissue, especially thymic epithelial cells. In addition, it also exists in lymphoid tissues (such as the spleen, lymph nodes) and non lymphoid tissues (such as the lungs, kidneys, and brain), and its secretion and release are not regulated by other hormones or release factors. thymus α 1 is easily degraded and inactivated in the body, with a short half-life (<2 hours). Although the thymus gland α The exact immune mechanism is not yet clear, but a large number of experiments have confirmed that it has a strong immune regulatory effect. It is a cellular immune enhancer and biological response regulatory factor, with immune regulatory effects, and is very important in the body's immune response process.1. Immunomodulatory effectsIt is now believed that thymosin α The mechanism of regulating immune response is mainly achieved through T cells, including increasing T cell production (CD3+, CD4+, CD8+cells), stimulating T cell differentiation and maturation, reducing T cell apoptosis, and producing T cell-mediated antibodies. In addition, the thymus gland α By regulating inflammatory cytokines (IL-2, IL-3, IL-6, IL-7, etc.) and interfer α, interfer γ (IFN - α, IFN - γ) Release and promote the differentiation and maturation of natural killer cells and dendritic cells.2. Antitumor effectsThymic peptide α 1. It has the value of treating various tumors. The functional status of the body's immune system, especially cellular immunity, is closely related to the occurrence, development, and patient prognosis of tumors. Conventional anti-tumor treatments (such as surgery, radiotherapy, etc.) can suppress cellular immunity, and T cell subsets are an important component of the body's immune defense system, playing a significant role in tumor immune monitoring and immune response. thymus α 1 is a peptide substance that can promote the generation of lymphocytes in the body, regulate the proportion of T cell subsets, promote B cell differentiation and antibody production, enhance the phagocytic function of macrophages, and ultimately improve the cellular immune system function of tumor patients.3. Other functionsThymic peptide α As a good anti-inflammatory factor, 1 can increase the number and activity of T cells, stimulate the production of other antiviral lymphokines and macrophages, and enhance phagocytic function, enabling the body to clear bacteria, fungi, and viruses. In addition, a large number of clinical trials have confirmed that the thymus gland α The thymus gland can effectively treat human viral diseases, such as viral hepatitis, cytomegalovirus, influenza, certain bacteria such as mycobacteria, and fungal diseases, by combining and/or regulating other biological effects (BRMs) alone α As an immune modulator, it promotes the decrease of pro-inflammatory cytokines while regulating the patient's own immunity, which can alleviate the damage caused by the patient's inflammatory state and inflammatory mediators. thymus α In addition to activating immune effector cells or regulating the expression of cytokines, it can also exert its effects by directly acting on target cells to inhibit virusesOur Advantages: High purity, Wholesale price, large stock, Stealth Shipping, 100% Delivery Guarantee Company ProfileZB Bio has a long-standing track record in with successful registrations of highly purified synthetic peptide drugs of the glucagon family. Our regulatory intelligence keeps track of important changes in the relevant legislation. This enables us to be a leading global innovator in the field of glucagon and glucagon-like synthetic peptide drugs. Our services have been optimized to shorten timelines and of reduce complexity for our clients.Our high-tech Good Manufacturing Practice (GMP) facilities based in Zhejiang province china, plus the commitment of our technical and scientific experts to quality, are the cornerstones for continuous compliance. We deliver small-scale to multi-kg active pharmaceutical ingredients (APIs) with impurities below 0.5%, identification and characterization of impurities above 0.10% using orthogonal analytical techniques.OPTIMIZED, AUTOMATED HIGH-YIELD PRODUCTIONOur long experience in complex APIs allows us to optimize the processes for high yields at outstanding quality. Our high level of process automation allows for cost-efficient and large-scale production resulting in excellent overall material purity (>99.5%). Innovative solutions like continuous chromatography let us use equipment and resources more efficiently and help us and our partners to achieve their commitment to sustainability and environment-friendly production. Packaging & ShippingOur Advantages FAQ1. Are you a manufacturer or trading company?A: We are a manufacturer and welcome to visit our factory. 2. How to confirm the product quality before placing an order?A: We can provide you with the sample. Also, we have the inspection report issued by the authoritative third-party testing agency. 3: What's your MOQ?A: It depends on different products. We accept sample orders. Also for some products, we can provide you with a free sample. 4:Do you provide after-sales service?A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us. 5:How about delivery time and method?A: We usually ship within 3-5 working days after payments. We can make ships by sea, air, and express. Also can make door-to-door shipping. 6:How to solve the after-sale disputes?A: We accept changing or refunding services if there is any quality problem.

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