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Pharmaceutical CAS 51481-65-3 Mezlocillin API Mezlocillin Powder Antibiotics Mezlocillin1
Pharmaceutical IntermediateMezlocillinCAS 51481-65-3 Mezlocillin
Xi'an Qiushi Co., Ltd.
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Product Description Pharmaceutical CAS 51481-65-3 Mezlocillin API Mezlocillin Powder Antibiotics MezlocillinProduct DescriptionProduct DetailsProduct NameMezlocillinApperanceWhite PowderCAS51481-65-3MFC21h25n5o8s2MW539.58Mezloxillin is a semi synthetic broad-spectrum penicillin antibiotic, with the chemical name (2S, 5R, 6R) -3,3-dimethyl-6- [(R) -2- (3-methylsulfonyl-2-oxoimidazolin-1-carboxamido) -2-phenylacetamido] -7-oxo-4-thio-1-azabicyclo [3.2.0] heptan-2-carboxylic acid. Its CAS number is 51481-65-3, molecular formula is C21H25N5O8S2, and molecular weight is 539.58. This product is a white or off white crystalline powder that is easily soluble in water and suitable for injection administration. Mezlocillin has significant antibacterial activity against various Gram negative bacteria and some Gram positive bacteria, especially against Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae. It is mainly used clinically to treat severe bacterial infections.Application&FunctionMezloxillin exerts bactericidal effects by inhibiting the synthesis of bacterial cell walls. Its structure is similar to penicillin, and it can specifically bind to penicillin binding proteins (PBPs) on bacterial cell membranes, interfere with peptidoglycan cross-linking, lead to cell wall defects, and ultimately cause bacterial rupture and death. It is less stable to β - lactase and is often used in combination with β - lactase inhibitors to enhance therapeutic efficacy. Mezlocillin has a wide antibacterial spectrum, especially effective against aerobic Gram negative bacteria (such as Enterobacteriaceae) and Pseudomonas aeruginosa, and is suitable for the treatment of respiratory, urinary, abdominal, and sepsis infections. It has a short half-life and needs to be administered in divided doses to maintain effective blood drug concentration.SpecificationABOUT US
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