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CIPDBChina IndustryChemicalsPharmaceutical Intermediate



Antioxidant 99% Pyrroloquinoline Quinone (PQQ) Powder CAS 72909-34-31

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Pharmaceutical IntermediatePQQ
Methoxatin (PQQ acid)
PQQ Acld

Xi'an Sentian Biotechnology Co., Ltd.

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Product Description Product Description Product name pyrroloquinoline quinone PQQFromPowderMOQ10GAppearancered powderPackage 1KG/Bag,5kg/bag,25kg/drumPlace of OriginShaan'Xi,ChinaThe scientific name of the PQQ pyrroloquinoline quinone (PQQ) pyrroloquinoline quinone is a new prosthetic group, is the second flavin nucleotides (FMN, FAD) and nicotinamide nucleotide (MAD NADP) in the membrane boundfound in the bacterial dehydrogenase third cofactor, the world's medical profession called fourteenth vitamins. The compound was first isolated from bacteria out, and then moving the plants have also been found, its chemical name is 4,5 - dihydro-4 ,5 - dioxide -1 - pyrrolo (2,3 f) The quinone -2,7,9-tricarboxylic acid, also known as methaxatin.Application & FuntionPyrroloquinoline quinone (henceforth PQQ) is a small quinone molecule which has the ability to be a REDOX agent, capable of reducing oxidants (an antioxidant effect) and then being recycled by glutathione back into an active form. It appears to be quite stable as it can undergo several thousand cycles before being used up, and it is novel since it associates with protein structures inside the cell (some antioxidants, mostly notably carotenoids like β-carotene and Astaxanthin, are located at specific areas of a cell where they exert proportionally more antioxidant effects due to proximity; PQQ seems to do this near proteins like carotenoids do so at the cell membrane). PQQ is present in nanomolar quantities in most foods and in most animal tissuse. It promotes growth, mitochondrial function, and development in vivo and stimulates cell proliferation and viability in culture. It is a potent antioxidant that scavenges superoxide and peroxinitrite. It is neuroprotectant against 6-hydroxydopamine-induced and hypoxia/ischemia-induced neurotoxicity. PQQ conjugates to α-synuclein in vitro, inhibiting the formation of amyloid fibrils1. Improve the body's immune functionAs a necessary factor of human development, it can stimulate the growth of cells in the body, especially the activation of human B cells, T cells, antibody production, improve the immune function of human body.Pyrroloquinoline Quinone is the most powerful bioactive substances so far. 2. Prevent and treat the liver damageCan significantly reduce serum bilirubin, alanine aminotransferase levels, make liver function normal, regulate liver damage and have very good curative effect on liver disease. 3. Reduce free radical damage to human bodyPQQ is a kind of oxidoreductase prosthetic group, involved in biological REDOX reaction in the body, can effectively remove free radicals in the body, reduce the harm of human body free radical, protect tissues, reduce the body damage caused by various diseases, such as heart disease, cancer and all kinds of inflammation.Free radicals is the source of diseases. 4. Regulate various neurological diseasesPyrroloquinoline Quinone is a new kind of water-soluble vitamins, can promote the synthesis of neural factors in the human body, regulate various neurological diseases. 5. Promote the absorption of amino acidsPyrroloquinoline Quinone is the prosthetic group of quinone protease, participate in the respiratory electron transport chain, in the human body through the effect of glucose, can promote the absorption of amino acids.Amino acid composition of cell SAP and synthetic protein peptide is the main raw material, is an important part of the body's biological active substances. 6. Promote the synthesis of GFGF can stimulate biological growth, can stimulate human body cell growth, increase the cell density.Trace amounts of Pyrroloquinoline Quinone could improve the biological function of the organization's ability to metabolize and growth.Why can slow the aging? 7. Prevent and treat the alzheimer's diseasePyrroloquinoline Quinone special biological activity and physiological function but also has the repair nerve fibers, the activation of neurons, activate the dormancy of the nerve cells, can effective prevention and treatment of alzheimer's disease and improve memory.Can effectively improve intelligence. 8. Promote the synthesis of glutathioneGlutathione by glutamic acid, cysteine and glycine combination of three peptides, has an important antioxidant effect, integrating detoxification, harmful to the body poison into harmless substance, excreted in vitro, glutathione is bioactive enhancer.Pyrroloquinoline Quinone can promote the body's glutathione synthesis, prevent and accumulation of hepatic bilirubin in cataract. 9. Strong anticancer function1. the activation of NK cells for ANK, make its have kill tumor;2. can make the NK cells and other immune cells gathered themselves together, and play a corps of operational capability, more effectively kill tumor cells;3. closed tumor cells carrying iron protein receptors, blocking its function, inhibiting tumor growth and metastasis;4. destroy the tumor cell lipid double, to dissolve tumor cell death;5. prevent tumor cell DNA replication, and promote its apoptosis;6. scavenging free radicals, prevent cancer, heart disease, etc.  COAItemsRequirementsResults   Physical & Chemical  AppearanceRed powderConformOdor CharacteristicCharacteristicParticle Size98% pass 80meshCompliesLoss on Drying≤5.0%3.65%Ash≤5.0%1.96%Solvent ResidueMeet USP standardCompliesPesticide ResidueMeet USP standardComplies   Heavy Metal  Lead (Pb)≤2.0ppmConform (As)≤1.0ppmConform (Cd)≤1.0ppmConform (Hg)≤0.1ppmConform   Microorganism  Total Plate Count≤1000cfu/gConformYeasts and Molds≤100cfu/gConformSaimonellaNegative/25gConformE.coliNegativeConform      Assay98%98.5%   Conclusion:This product conforms to the Enterprise standard.Company

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